Hyperosmolality regulates UT-A6 urea transporter expression in the Caco-2 cell line
نویسندگان
چکیده
منابع مشابه
Hyperosmolality regulates UT‐A6 urea transporter expression in the Caco‐2 cell line
Gastrointestinal facilitative urea transporters play a significant role in the urea nitrogen salvaging process, which supports the symbiotic relationship between mammals and their gut microbial populations. UT-A6 urea transporters have been previously reported in the human gastrointestinal tract, specifically in the colon. As renal UT-A transporters can be regulated by external osmolality, this...
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Production, recycling, and elimination of urea are important to maintain nitrogen balance. Adaptation to varying loads of urea due to different protein intake or in renal failure may involve changes in urea transport and may possibly affect urea transporters. In this study, we examined the expression of the UT-B urea transporter in rats fed a low-protein diet (LPD), a high-protein diet (HPD), a...
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The UT-B urea transporter is the major urea transporter in red blood cells and kidney descending vasa recta. Humans and mice that lack UT-B have a mild urine-concentrating defect. Whether deletion of UT-B altered the expression of other transporter proteins involved in urinary concentration was tested. Fluorescence-based real-time reverse transcription-PCR and Northern blot analysis showed upre...
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ژورنال
عنوان ژورنال: Physiological Reports
سال: 2016
ISSN: 2051-817X
DOI: 10.14814/phy2.12984